*Co-first authors #Corresponding author(s) Shikuma Lab Members
AT Alker, N Delherbe, T Purdy, B Moore, NJ Shikuma (2020). Genetic examination of the marine bacterium Pseudoalteromonas luteoviolacea and effects of its metamorphosis-inducing factors. Environmental Microbiology. https://doi.org/10.1111/1462-2920.15211
We uncover a hidden complexity of interactions between a single bacterial species, the factors it produces and two species of animal larvae.
GS Cavalcanti, AT Alker, N Delherbe, KE Malter, NJ Shikuma (2020). The Influence of Bacteria on Animal Metamorphosis. Annual Review of Microbiology. 74:137-58. https://doi.org/10.1146/annurev-micro-011320-012753
We review what is known and what we hope to learn about how bacteria and the factors they produce stimulate animal metamorphosis.
Maria I. Rojas*, Giselle S. Cavalcanti*, Katelyn McNair, Sean Benler, Amanda T. Alker, Ana G. Cobián-Güemes, Melissa Giluso, Kyle Levi, Forest Rohwer, Barbara Bailey, Sinem Beyhan, Robert A. Edwards, Nicholas J. Shikuma (2020). A Distinct Contractile Injection System Gene Cluster Found in a Majority of Healthy Adult Human Microbiomes. mSystems 5:e00648-20. https://doi.org/10.1128/MSYSTEMS.00648-20
We discovered a yet undescribed Injection System genecluster in the microbiomes of nearly all adult humans.
CEricson*, FEisenstein*, J Medeiros, K Malter, G Cavalcanti, RW Zeller, DK Newman, MPilhofer# andNJShikuma# (2019). A Contractile Injection System Stimulates Tubeworm Metamorphosis by Translocating a Proteinaceous Effector. eLife 8:e46845.https://doi.org/10.7554/eLife.46845.
I Rocchi*, C Ericson*, KE Malter*, S Zargar, F Eisenstein, M Pilhofer, S Beyhan# and NJ Shikuma# (2019). A Bacterial Phage Tail-like Structure Kills Eukaryotic Cells by Injecting a Nuclease Effector. Cell Reports 28(2), 295-301.https://doi.org/10.1016/j.celrep.2019.06.019.
NJ Shikuma, JCN Fong and FH Yildiz (2012) Cellular levels and binding of c-di-GMP control subcellular localization and activity of the Vibrio cholerae transcriptional regulator VpsT. PLoS Pathogens 8(5):e1002719.
PV Krasteva, JCN Fong, NJ Shikuma, S Beyhan, MVAS Navarro, FH Yildiz and H Sondermann (2010)Vibrio cholerae VpsT regulates matrix production and motility by directly sensing cyclic di-GMP. Science 327:866-868.
NJ Shikuma and FH Yildiz (2009) Identification and characterization of OscR, a transcriptional regulator involved in osmolarity adaptation in Vibrio cholerae. Journal of Bacteriology191:4082-4096.